What are the effects? Kratom is a rather unique drug in that a low to moderate dose will usually (but not always) be stimulating, while a high dose is almost always quite sedating. This is apparently because the active alkaloids (primarily mitragynine) have both stimulant and sedative effects. Which predominates probably depends both on blood level and individual differences between users. The stimulant level: At the stimulant level the mind is more alert, physical energy and sometimes sexual energy is increased, ability to do hard monotonous physical work may be improved, one is more talkative, friendly, and sociable. Some people find this level edgy rather than pleasant. The sedative-euphoric-analgesic level: At this dosage you will be less sensitive to physical or emotional pain, feel and look calm, have a general feeling of comfortable pleasure, and may enter a pleasant dreamy reverie. You may experience some itching or sweating. Your pupils may be constricted (small). It is possible you may feel nauseated, but if you lie down the nausea should quickly cease. You may find your appreciation of music is increased. It will be very pleasant to lie down on your back in a semi-darkened room, with eyes closed, and just listen to your favorite music. If you do this you may be fortunate enough to enter the delightful mixed-state of ‘waking-dreaming’ where you have one foot in dreamland and the other foot in the real world. This state was much prized by the 19th century Romantic writers, who, lacking knowledge of kratom, resorted to the much more habit-forming narcotic, opium, to achieve it. The effects of kratom usually last about six hours. The higher the dose, the stronger the effects, and the longer they last. Many people report a positive ‘afterglow’ the next day. (Text by "Sage Student" and Daniel Siebert)